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M J Kreek Selected Research

Methadone (Dolophine)

10/2019Current status of opioid addiction treatment and related preclinical research.
8/2012Nerve growth factor β polypeptide (NGFB) genetic variability: association with the methadone dose required for effective maintenance treatment.
1/2012Integrated internist - addiction medicine - hepatology model for hepatitis C management for individuals on methadone maintenance.
7/2009Heroin addiction in African Americans: a hypothesis-driven association study.
12/2008Steady-state methadone effect on generalized arousal in male and female mice.
10/2008Genetic susceptibility to heroin addiction: a candidate gene association study.
4/2008Genotype patterns that contribute to increased risk for or protection from developing heroin addiction.
5/2001Altered HPA axis responsivity to metyrapone testing in methadone maintained former heroin addicts with ongoing cocaine addiction.
12/2000Opioid receptor imaging with positron emission tomography and [(18)F]cyclofoxy in long-term, methadone-treated former heroin addicts.
11/2000Lethal methadone intoxications in Geneva, Switzerland, from 1994 to 1998.
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M J Kreek Research Topics

Disease

7Heroin Dependence (Heroin Abuse)
08/2012 - 01/2000
6Substance-Related Disorders (Drug Abuse)
07/2014 - 11/2000
6Cocaine-Related Disorders (Cocaine Addiction)
01/2013 - 07/2000
4Opioid-Related Disorders (Opiate Addiction)
10/2019 - 10/2000
2Alcoholism (Alcohol Abuse)
08/2001 - 05/2001
1Anhedonia
05/2022
1Cancer Pain
10/2019
1Chronic Pain
10/2019
1Binge Drinking
01/2017
1Thymoma (Thymic Carcinoma)
01/2015
1AIDS-Related Complex (ARC)
04/2013
1Mood Disorders (Mood Disorder)
09/2012
1Hepatitis C
01/2012
1Hepatitis
01/2012
1Chronic Hepatitis C
04/2009
1Herpes Simplex
09/2001
1Dementia (Dementias)
03/2001
1Alzheimer Disease (Alzheimer's Disease)
03/2001
1Seizures (Absence Seizure)
03/2001
1Ischemia
03/2001
1Pain (Aches)
12/2000
1Personality Disorders (Personality Disorder)
01/2000

Drug/Important Bio-Agent (IBA)

12Methadone (Dolophine)FDA LinkGeneric
10/2019 - 01/2000
8Heroin (Diamorphine)IBA
07/2014 - 01/2000
8Opioid Analgesics (Opioids)IBA
01/2013 - 01/2000
5Pharmaceutical PreparationsIBA
10/2003 - 01/2000
4mu Opioid Receptors (mu Opioid Receptor)IBA
04/2008 - 01/2000
3kappa Opioid Receptors (kappa Opioid Receptor)IBA
05/2022 - 03/2001
3Pro-Opiomelanocortin (Proopiomelanocortin)IBA
01/2017 - 09/2001
3Messenger RNA (mRNA)IBA
01/2015 - 09/2001
3Opiate AlkaloidsIBA
04/2009 - 01/2000
2Naloxone Drug Combination BuprenorphineFDA Link
10/2019 - 01/2000
2Analgesics (Analgesic Drugs)IBA
10/2019 - 01/2000
2Opioid Receptors (Opioid Receptor)IBA
01/2013 - 09/2001
2Peptides (Polypeptides)IBA
08/2012 - 09/2001
2Cocaine (Cocaine HCl)IBA
08/2010 - 08/2001
1AticaprantIBA
05/2022
1Ionotropic Glutamate ReceptorsIBA
01/2015
1Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA
01/2015
1Mitogen-Activated Protein KinasesIBA
01/2015
1Oxycodone (Oxycontin)FDA LinkGeneric
01/2015
1Dopamine (Intropin)FDA LinkGeneric
01/2013
1Serotonin (5 Hydroxytryptamine)IBA
01/2013
1NeuropeptidesIBA
01/2013
1OrexinsIBA
01/2013
1Glutamic Acid (Glutamate)FDA Link
01/2013
1Vasopressins (Vasopressin)IBA
01/2013
1Dynorphins (Dynorphin)IBA
09/2012
1Nerve Growth Factor (NGF)IBA
08/2012
1Nerve Growth Factors (Neurotrophins)IBA
08/2012
1RNA (Ribonucleic Acid)IBA
01/2012
1fatty-acid amide hydrolase (fatty acid amide hydrolase)IBA
06/2010
1Cannabinoid Receptors (Cannabinoid Receptor)IBA
06/2010
1myocardinIBA
04/2008
1DNA (Deoxyribonucleic Acid)IBA
04/2008
1Transcription Factors (Transcription Factor)IBA
04/2008
1Deoxyribodipyrimidine Photo-LyaseIBA
04/2008
1metabotropic glutamate receptor 6IBA
04/2008
1metabotropic glutamate receptor 8IBA
04/2008
1CryptochromesIBA
04/2008
1Member 2 Group A Nuclear Receptor Subfamily 4IBA
04/2008
1Thymidine KinaseIBA
09/2001
1Illicit Drugs (Recreational Drugs)IBA
08/2001
15-HT1B Serotonin ReceptorIBA
08/2001
1MetyraponeFDA Link
05/2001
1GlucocorticoidsIBA
05/2001
1delta Opioid Receptors (delta Opioid Receptor)IBA
03/2001
1Hydrocortisone (Cortisol)FDA LinkGeneric
03/2001
16-deoxy-6-fluoronaltrexoneIBA
12/2000
1Amino AcidsFDA Link
10/2000
1Biological ProductsIBA
01/2000
1Morphine (MS Contin)FDA LinkGeneric
01/2000
1Methadyl Acetate (LAAM)FDA Link
01/2000

Therapy/Procedure

3Drug Therapy (Chemotherapy)
10/2019 - 01/2000
3Self Administration (Administration, Self)
01/2015 - 07/2000